Butler County Vacations & Trips from $368

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Your Butler County Vacation

Answer the call of adventure with a customized vacation package to Butler County. Wherever it is you're headed and whatever you have planned, get ready to immerse yourself in a destination that'll make you truly feel alive. A trip to Butler County offers lots of things to see and do. Not sure where to begin? Poplar Bluff is one of the most popular cities to stay here. From the instant you book your Butler County vacation to when you get back home, Expedia has you covered every step of the way.

Top destinations in Butler County

A sunset over a calm lake with red autumn leaves on the right.

Poplar Bluff

Poplar Bluff

The Latest Butler County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

$368
per person
Sep 18 - Sep 20
found 4 hours ago
Roundtrip non-stop flight included
Los Angeles (QLA) to Cape Girardeau (CGI)
8/10 Very Good! (1,007 reviews)
University Inn of Carbondale by Hotel O

University Inn of Carbondale by Hotel O

$666
per person
Sep 21 - Sep 23
found 1 day ago
Roundtrip flight included
Monroe (MLU) to Cape Girardeau (CGI)
5.8/10 (401 reviews)
it was being constructed!

Reviewed on Aug 11, 2026

The Riverview

The Riverview

$724
per person
Oct 29 - Nov 1
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Cape Girardeau (CGI)
9.4/10 Exceptional! (638 reviews)
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

$741
per person
Oct 29 - Nov 1
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Cape Girardeau (CGI)
9.6/10 Exceptional! (1,008 reviews)
Staff was very nice and helpful will stay again

Reviewed on Aug 16, 2026

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

$862
per person
Sep 21 - Sep 23
found 1 day ago
Roundtrip non-stop flight included
Monroe (MLU) to Cape Girardeau (CGI)
9.4/10 Exceptional! (105 reviews)

Find the Best Butler County Vacation Packages

Butler County Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)

Butler County Hotel Deals

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$79 nightly
$88 total
Aug 19 - Aug 20
Total with taxes and fees
Motel 6 Poplar Bluff, MO
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

3109 Oak Grove Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$101 nightly
$114 total
Aug 23 - Aug 24
Total with taxes and fees
9.4/10 Exceptional! (952 reviews)
"Clean room help staff basic breakfast, but was good parking. Plenty easy to reach."

Reviewed on Aug 13, 2026

Fairfield Inn & Suites by Marriott Poplar Bluff
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$92 nightly
$104 total
Aug 23 - Aug 24
Total with taxes and fees
Drury Inn & Suites Poplar Bluff
See all 110 properties in Butler County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Butler County attractions

Black River Coliseum

8.2/10 (30 reviews)
Catch an event at Black River Coliseum during your trip to Poplar Bluff. While in this family-friendly area, you can enjoy the restaurants.
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North Main Street Historic District

You can find out about the history of Poplar Bluff with a trip to North Main Street Historic District. While in this family-friendly area, you can enjoy the restaurants.
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Mo-Ark Regional Railroad Museum

6.8/10 (13 reviews)
You can study the exhibits at Mo-Ark Regional Railroad Museum, a museum with a storied past, during your travels to Poplar Bluff. While in this family-friendly area, you can enjoy the restaurants.
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Ozark Ridge Golf Course

7.4/10 (3 reviews)
Enjoy a round of golf in Poplar Bluff at Ozark Ridge Golf Course. Take in the entertainment venues and waterfalls in the area.
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Redman Creek Recreation Area

Explore the great outdoors at Redman Creek Recreation Area, a lovely green space in Wappapello.
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Margaret Harwell Art Museum

5.8/10 (8 reviews)
You can study the exhibits at Margaret Harwell Art Museum, a museum with a storied past, during your travels to Poplar Bluff. Stroll along the riverfront or experience the entertainment venues in this family-friendly area.
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Rockwood Point Recreation Area

Explore the great outdoors at Rockwood Point Recreation Area, a lovely green space in Wappapello.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.